ABSTRACT
Indonesia declares COVID-19 Pandemic by the World Health Organization (WHO) from March 2020. This has a very impact, one of which is on the continuity of the world of education. This research aims to foretell the impact of hybrid teaching methods used at SMK Cendikia Cirebon City during the COVID-19 period on student achievement. Teachers' materials, honesty, enthusiasm, and IT backing are all factors in determining the quality of education. Multiple linear regression with root-mean-squared error as the dependent variable is used in this study (RMSE). Experiments conducted on 122 participants yielded an RMSE of 0.375 and a correlation level of 0.440 for each attribute, with test samples comprising 10% and training samples comprising 90%. As a result, the use of this multiple linear regression model can be suggested for foreseeing the introduction of a hybrid learning model to enhance educational quality. © 2023 International Information and Engineering Technology Association. All rights reserved.
ABSTRACT
BACKGROUND: COVID-19 is a condition that is characterized by an abnormal coagulation state, which is a reason for severe thrombotic problems. AIM: We aim to determine the correlation of coagulation parameters levels with clinical outcomes of critically ill patients with COVID-19 admitted to intensive care at a national referral hospital in Indonesia. METHOD(S): This retrospective cohort study analyzed 227 patients with a primary diagnosis of COVID-19 on mechanical ventilation who were admitted to the COVID-19 intensive care unit, Dr. M. Djamil from 2020 to 2021 taken in the medical record. Numerical data were analyzed using an independent t-test, while the categorical data were analyzed using the Chi-square test. RESULT(S): One hundred and one patients were >65 years old. The mean +/- SD of INR levels, D-dimer levels, and platelet count on the first and the 5th days were 1.22 +/- 0.77 and 1.36 +/- 1.16;4.624 +/- 3.533 microg/L and 4.334 +/- 3.365 microg/L;and 160.162 +/- 117.203/microl and 234.070 +/- 126.816/microl. There was a significant correlation between age (p = 0.002), INR levels on the 5th day (p = 0.041), platelet count on the 5th day (0.012) with clinical outcomes of patients. CONCLUSION(S): There is a significant increase in the average platelets and INR levels on day 5. There is a significant correlation between INR levels and platelet count on 5th days with clinical outcomes of patients. Copyright © 2022 Dedy Kurnia, Eti Yerizel, Andani Ekaputra, Dwitya Elvira.
ABSTRACT
BACKGROUND: Approximately 14–50% of severe COVID-19 patients are admitted to the Intensive Care Unit (ICU) that acquires a multidrug-resistant bacterial infection (MDR) and worsens clinical outcomes of patients. AIM: We aim to determine the increased risk of MDR infection in the ICU including large-spectrum antibiotic administration, invasive procedure performance (mechanical ventilation), and clinical outcomes of patient. METHODS: We analyzed 227 patients with a primary diagnosis of COVID-19 on mechanical ventilation who were admitted to ICU COVID-19 RSUP Dr. M. Djamil from 2020 to 2021. Demographic information, sputum culture results, intubation, and clinical outcomes were all collected in the medical records for this retrospective cohort study. Patients who were hospitalized for <48 h in the ICU were excluded from the study. An independent t-test and a Chi-square test were used to analyze the data. RESULTS: In sixty patients (26.4%), bacteria were found in the sputum culture, 40 patients (66.7%) of them were MDR. The most common bacteria found was Acinetobacter baumanii (35%) followed by Klebsiella pneumonia (21.7%). There is a significant relationship between MDR (p-value 0.000) and intubation (p-value, 000) to clinical outcomes of patients (improvement or death). There is a significant relationship between intubation and MDR (p-value 0.009). CONCLUSION: MDR patient status affected the outcomes of COVID-19 patients in the ICU. Patients with MDR were more likely to have a poor clinical outcome.